2-((tetrahydro-2H-pyran-2-yl)oxy)ethanol -Drug Synthesis Database

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【结构式】

【分子编号】69576

【品名】2-((tetrahydro-2H-pyran-2-yl)oxy)ethanol

【CA登记号】

【分子式】C₇H₁₄O₃

【分子量】146.18636

【元素组成】C 57.51% H 9.65% O 32.83%

与该中间体有关的原料药合成路线共 1 条

合成路线1

合成路线1

该中间体在本合成路线中的序号：(III)

　

参考文献中间体

【1】 Artus Surroca JJ,Janet Bonet M,Rafecas Jane L.Intermediate compounds for obtaining main active anti-hypertensive agents together with corresponding procedures:ES,Patent 2,211,317,2004.
【2】 Yiu SH,Knaus EE.Synthesis,calcium channel antagonist activity,and anticonvulsant activity of 3-ehtyl 5-methyl 1,4-dihydro-2-[(2-hydroxyethoxy)methyl]-6-methyl-4-(2,3-dichloro-phenyl)-3,5-pyridinedicarboxylate coupled to a 1-methyl-1,4-dihydropyridyl-3-carbonyl chemical delivery system. Arch Pharma,1999,332:363.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	11295	Polyethylene glycol;1,2-Ethanediol;Monoethylene glycol; Ethylene glycol	107-21-1	C₂H₆O₂	详情	详情
(II)	13684	3,4-Dihydro-2H-pyran;2,3-Dihydro-4H-pyran; 5,6-Dihydro-4H-pyran;Dihydropyran	110-87-2	C₅H₈O	详情	详情
(III)	69576	2-((tetrahydro-2H-pyran-2-yl)oxy)ethanol		C₇H₁₄O₃	详情	详情
(IV)	23541	ethyl 4-chloro-3-oxobutanoate；Ethyl 4-chloro-3-oxobutanoate；Ethyl 4-chloroacetoacetate	638-07-3	C₆H₉ClO₃	详情	详情
(V)	69577	ethyl 3-oxo-4-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)butanoate		C₁₃H₂₂O₆	详情	详情
(VI)	69578	ethyl 4-(2-hydroxyethoxy)-3-oxobutanoate		C₈H₁₄O₅	详情	详情
(VII)	44034	methyl (Z)-2-acetyl-3-(2-chlorophenyl)-2-propenoate		C₁₂H₁₁ClO₃	详情	详情
(VIII)	69579	3-ethyl 5-methyl 4-(2-chlorophenyl)-2-((2-hydroxyethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate		C₂₀H₂₄ClNO₆	详情	详情
(IX)	69580	3-ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-((2-((methylsulfonyl)oxy)ethoxy)methyl)-1,4-dihydropyridine-3,5-dicarboxylate		C₂₁H₂₆ClNO₈S	详情	详情
(X)	69570	Benzenesulfonic acid;Phenylsulfonic acid;Benzenemonosulfonic acid;Benzensulfonic acid;Benzenesulphonic acid;	98-11-3	C₆H₆O₃S	详情	详情

Extended Information