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【结 构 式】

【分子编号】67076

【品名】2-(4-(benzyloxy)phenyl)acetyl chloride

【CA登记号】 

【 分 子 式 】C15H14ClO2

【 分 子 量 】261.728

【元素组成】C 68.84% H 5.39% Cl 13.55% O 12.26%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号: (II)

 

1 Gore VG, Kulkarni VS, Wakchaure VS, et al. 2008. Process for perparation of O-desmethyl venlafaxine(ODV) from phenylacetic acid derivatives, dimethylamino, and cyclohexanone. WO 2008093142.
2 Niddam-Hildesheim V, Shenkar N, Shachan-Tov S. 2008. Process for the synthesis of O-desmethylvenlafaxine from 1-[2-amino-1-(4-methoxyphenyl) ethyl] cyclohexanol via O-demethylation and N-methylation reactions. WO 2008013995.
3 Niddam-Hildesheim V, Shenkar N, Shachan-Tov S. 2008. Process for the synthesis of O-desmethylvenlafaxine from hydroxybenzyl cyanide via condensation reaction with cyclohexanone. WO 2008013993.
4 Niddam-Hildesheim V, Shenkar N, Shachan-Tov S. 2008. Process for the synthesis of O-desmethylvenlafaxine from (4-hydroxyphenyl) acetic acid. WO 2008013990.
5 Zupancic S, Skrabanja V. 2007. Process for praparation of O-desmethylvenlafaxine. WO 2007147564.
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(II) 67076 2-(4-(benzyloxy)phenyl)acetyl chloride   C15H14ClO2 详情 详情
(I) 67075 2-(4-(benzyloxy)phenyl)acetic acid   C15H14O3 详情 详情
(III) 67077 2-(4-(benzyloxy)phenyl)-N,N-dimethylacetamide   C17H20NO2 详情 详情
(IV) 11059 Cyclohexanone 108-94-1 C6H10O 详情 详情
(V) 67078 2-(4-(benzyloxy)phenyl)-2-(1-hydroxycyclohexyl)-N,N-dimethylacetamide   C23H30NO3 详情 详情
Extended Information