2-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one -Drug Synthesis Database

【结构式】

【分子编号】66932

【品名】2-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

【CA登记号】　

【分子式】C₂₁H₂₈N₆O₄S

【分子量】462.548

【元素组成】C 54.96% H 6.10% N 18.17% O 13.84% S 6.93%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(V)

【1】 Seidel D. Brehmer P, Schoof Y. et al. 2003. Synthesis of ¹⁴C-labelled vardenafil hydrochloride and metabolites. J Label Camp Radiopharm, 46 (11): 1019～1032

中间体序号	中间体编号	品名	分子式	供应商	用于合成
(I)	66927	2-(2-ethoxyphenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one	C₁₇H₂₀N₄O₂	详情	详情
(II)	66928	4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride	C₁₇H₁₉ClN₄O₄S	详情	详情
(III)	66930	4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonic acid	C₁₇H₂₀N₄O₅S	详情	详情
(IV)	66931	4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonamide	C₁₇H₂₁N₅O₄S	详情	详情
(V)	66932	2-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one	C₂₁H₂₈N₆O₄S	详情	详情
(VI)	66933	4-ethoxy-N-(2-(ethylamino)ethyl)-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonamide	C₂₁H₃₀N₆O₄S	详情	详情
(VII)	66934	N-(2-aminoethyl)-4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonamide	C₁₉H₂₆N₆O₄S	详情	详情

Extended Information