4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride -Drug Synthesis Database

【结构式】

【分子编号】66928

【品名】4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride

【CA登记号】　

【分子式】C₁₇H₁₉ClN₄O₄S

【分子量】412.871

【元素组成】C 49.94% H 4.64% Cl 8.59% N 13.57% O 15.50% S 7.77%

与该中间体有关的原料药合成路线共 2 条

该中间体在本合成路线中的序号：(IX)

【1】 Seidel D. Brehmer P, Schoof Y. et al. 2003. Synthesis of ¹⁴C-labelled vardenafil hydrochloride and metabolites. J Label Camp Radiopharm, 46 (11): 1019～1032

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(XI)	66929	4-((4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)phenyl)sulfonyl)-1-ethylpiperazine 1-oxide hydrochloride		C₂₃H₃₂N₆O₅S.HCl	详情	详情
(I)	66921	2-iodophenol	30587-23-6	C₆H₅IO	详情	详情
(II)	66922	2-hydroxybenzonitrile		C₇H₅NO	详情	详情
(III)	66923	2-ethoxybenzonitrile		C₉H₉NO	详情	详情
(IV)	66924	2-ethoxybenzimidamide hydrochloride		C₉H₁₃ClN₂O	详情	详情
(VI)	66925	(Z)-3-butyramido-1-ethoxy-1-oxobut-2-en-2-yl ethyl oxalate		C₁₄H₂₁NO₇	详情	详情
(VII)	66926	(Z)-N-(1-(3-(2-ethoxyphenyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6(1H)-ylidene)ethyl)butyramide		¹⁴CC₁₆H₂₂N₄O₃	详情	详情
(VIII)	66927	2-(2-ethoxyphenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one		C₁₇H₂₀N₄O₂	详情	详情
(IX)	66928	4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride		C₁₇H₁₉ClN₄O₄S	详情	详情

该中间体在本合成路线中的序号：(II)

【1】 Seidel D. Brehmer P, Schoof Y. et al. 2003. Synthesis of ¹⁴C-labelled vardenafil hydrochloride and metabolites. J Label Camp Radiopharm, 46 (11): 1019～1032

中间体序号	中间体编号	品名	分子式	供应商	用于合成
(I)	66927	2-(2-ethoxyphenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one	C₁₇H₂₀N₄O₂	详情	详情
(II)	66928	4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride	C₁₇H₁₉ClN₄O₄S	详情	详情
(III)	66930	4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonic acid	C₁₇H₂₀N₄O₅S	详情	详情
(IV)	66931	4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonamide	C₁₇H₂₁N₅O₄S	详情	详情
(V)	66932	2-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one	C₂₁H₂₈N₆O₄S	详情	详情
(VI)	66933	4-ethoxy-N-(2-(ethylamino)ethyl)-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonamide	C₂₁H₃₀N₆O₄S	详情	详情
(VII)	66934	N-(2-aminoethyl)-4-ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonamide	C₁₉H₂₆N₆O₄S	详情	详情

Extended Information