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【结 构 式】 
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【分子编号】66529 【品名】 【CA登记号】 |
【 分 子 式 】C28H37NO4 【 分 子 量 】451.60612 【元素组成】C 74.47% H 8.26% N 3.1% O 14.17% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(V)
| 【1】 Neef G.Beier S,Elger W, et aL 1984. New steroids with antiprogestational and antiglucocorticoid activities Steroids, 44 (4): 349～372 |
| 【2】 Wiechert R.Ned G 1987. Synthesis of antiprogestational steroids. J Steroid Biochem, 27 (4-6): 851～858 |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 66526 | 13-methyl-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[5,10-epoxycyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-ol | C20H28O4 | 详情 | 详情 | |
| (II) | 10863 | Bromo[4-(dimethylamino)phenyl]magnesium | 7353-91-5 | C8H10BrMgN | 详情 | 详情 |
| (III) | 66527 | 11-(4-(dimethylamino)phenyl)-13-methyl-1,2,4,5,6,7,8,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-5,17-diol | C28H39NO4 | 详情 | 详情 | |
| (IV) | 66528 | 11-(4-(dimethylamino)phenyl)-5-hydroxy-13-methyl-1,2,5,6,7,8,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17(4H)-one | C28H37NO4 | 详情 | 详情 | |
| (V) | 66529 | C28H37NO4 | 详情 | 详情 | ||
| (VI) | 43835 | 2-propynyl tetrahydro-2H-pyran-2-yl ether; 2-(2-propynyloxy)tetrahydro-2H-pyran | 6089-04-9 | C8H12O2 | 详情 | 详情 |
| (VII) | 66530 | 11-(4-(dimethylamino)phenyl)-13-methyl-17-(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-yn-1-yl)-1,2,4,5,6,7,8,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-5,17-diol | C36H49NO6 | 详情 | 详情 |
Extended Information