tert-Butylchlorodiphenylsilane;tert-Butyldiphenylchlorosilane;tert-Butyldiphenylsilyl chloride -Drug Synthesis Database

【结构式】

【分子编号】66313

【品名】tert-Butylchlorodiphenylsilane;tert-Butyldiphenylchlorosilane;tert-Butyldiphenylsilyl chloride

【CA登记号】58479-61-1

【分子式】C₁₆H₁₉ClSi

【分子量】274.865

【元素组成】C 69.92% H 6.97% Cl 12.90% Si 10.22%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(II)

【1】 Liotta DC, Schinazi RF, et al.1993. The preparation of 2'-deoxy-5-fluoro-3'-thiacytidine and related compounds as anti-HIV nucleosides. US 5210085

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	12234	2-Propen-1-ol; Allyl alcohol	107-18-6	C₃H₆O	详情	详情
(II)	66313	tert-Butylchlorodiphenylsilane;tert-Butyldiphenylchlorosilane;tert-Butyldiphenylsilyl chloride	58479-61-1	C₁₆H₁₉ClSi	详情	详情
(III)	66314	(allyloxy)(tert-butyl)diphenylsilane		C₁₉H₂₄OSi	详情	详情
(IV)	44475	2-[[tert-butyl(diphenyl)silyl]oxy]acetaldehyde		C₁₈H₂₂O₂Si	详情	详情
(V)	18524	2-sulfanylacetic acid	68-11-1	C₂H₄O₂S	详情	详情
(VI)	66315	2-(((tert-butyldiphenylsilyl)oxy)methyl)-1,3-oxathiolan-5-one		C₂₀H₂₄O₃SSi	详情	详情
(VII)	55072	(2R)-2-({[tert-butyl(diphenyl)silyl]oxy}methyl)-1,3-oxathiolan-4-yl acetate		C₂₂H₂₈O₄SSi	详情	详情
(VIII)	36959	5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine; N-[5-fluoro-2-[(trimethylsilyl)oxy]-4-pyrimidinyl]-N-(trimethylsilyl)amine		C₁₀H₂₀FN₃OSi₂	详情	详情
(IX)	66316	4-amino-1-((2S,5R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-1,3-oxathiolan-5-yl)-5-fluoropyrimidin-2(1H)-one		C₂₄H₂₈FN₃O₃SSi	详情	详情

Extended Information