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【结 构 式】

【分子编号】39748

【品名】1,2-bis(aminooxy)ethane; O-[2-(aminooxy)ethyl]hydroxylamine

【CA登记号】

【 分 子 式 】C2H8N2O2

【 分 子 量 】92.0978

【元素组成】C 26.08% H 8.76% N 30.42% O 34.74%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(II)

The title compound was obtained by condensation between 9-ethylcarbazole-3-carboxaldehyde (I), veratraldehyde (III), and O,O'-diaminoethanediol (II). The desired asymmetric bisoxime was separated from the symmetric homodimers by silica gel column chromatography.

1 Choong, I.C.; Dustin, J.; Ellman, J.A.; Combinatorial target-guided ligand assembly: Identification of potent subtype-selective c-Src inhibitors. Proceedings of the National Academy of Sciences of the United States of America 2000, 97, 6, 2419.
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 39747 9-ethyl-9H-carbazole-3-carbaldehyde 7570-45-8 C15H13NO 详情 详情
(II) 39748 1,2-bis(aminooxy)ethane; O-[2-(aminooxy)ethyl]hydroxylamine C2H8N2O2 详情 详情
(III) 39749 3,4-dihydroxybenzaldehyde 139-85-5 C7H6O3 详情 详情
Extended Information