9-ethyl-9H-carbazole-3-carbaldehyde -Drug Synthesis Database

【结构式】

【分子编号】39747

【品名】9-ethyl-9H-carbazole-3-carbaldehyde

【CA登记号】7570-45-8

【分子式】C₁₅H₁₃NO

【分子量】223.27436

【元素组成】C 80.69% H 5.87% N 6.27% O 7.17%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(I)

The title compound was obtained by condensation between 9-ethylcarbazole-3-carboxaldehyde (I), veratraldehyde (III), and O,O'-diaminoethanediol (II). The desired asymmetric bisoxime was separated from the symmetric homodimers by silica gel column chromatography.

参考文献中间体

合成目标

【1】 Choong, I.C.; Dustin, J.; Ellman, J.A.; Combinatorial target-guided ligand assembly: Identification of potent subtype-selective c-Src inhibitors. Proceedings of the National Academy of Sciences of the United States of America 2000, 97, 6, 2419.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	39747	9-ethyl-9H-carbazole-3-carbaldehyde	7570-45-8	C₁₅H₁₃NO	详情	详情
(II)	39748	1,2-bis(aminooxy)ethane; O-[2-(aminooxy)ethyl]hydroxylamine		C₂H₈N₂O₂	详情	详情
(III)	39749	3,4-dihydroxybenzaldehyde	139-85-5	C₇H₆O₃	详情	详情

Extended Information