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【结 构 式】

【分子编号】29596

【品名】9-oxo-9H-fluorene-4-carbaldehyde

【CA登记号】

【 分 子 式 】C14H8O2

【 分 子 量 】208.21632

【元素组成】C 80.76% H 3.87% O 15.37%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(II)

Fluorenone-4-carboxaldehyde (II) was obtained by reduction of acid chloride (I). Subsequent Hantzsch synthesis using allyl acetoacetate (III) and ammonium hydroxide in boiling isopropyl alcohol provided the title dihydropyridine.

1 Valenti, P.; Brudiesi, R.; Rampa, A.; Chiarini, A.; Fluorenone and benzophenone 1,4-dihydropyridine derivatives with cardiodepressant activity. Arzneim-Forsch Drug Res 1992, 42, 11, 1284.
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 29595 9-oxo-9H-fluorene-4-carbonyl chloride C14H7ClO2 详情 详情
(II) 29596 9-oxo-9H-fluorene-4-carbaldehyde C14H8O2 详情 详情
(III) 22675 allyl 3-oxobutanoate 1118-84-9 C7H10O3 详情 详情
Extended Information