|
【结 构 式】 
|
【分子编号】22910 【品名】nicotinoyl chloride 【CA登记号】20260-53-1 |
【 分 子 式 】C6H5Cl2NO 【 分 子 量 】178.01724 【元素组成】C 40.48% H 2.83% Cl 39.83% N 7.87% O 8.99% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(III)L44 is prepared by alkylating p-cyclohexylphenol (I) with iosobutene using Aberlyst A 15 as a catalyst. The raw mixture (II) is esterified with nicotinoyl chloride hydrochloride (III). The product is purified by recristallization from ethanol.
| 【1】 Quack, G.; L44/L44-O. Drugs Fut 1987, 12, 4, 349. |
Extended Information