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【结 构 式】 
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【分子编号】22908 【品名】4-cyclohexylphenol 【CA登记号】1131-60-8 |
【 分 子 式 】C12H16O 【 分 子 量 】176.25844 【元素组成】C 81.77% H 9.15% O 9.08% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(I)L44 is prepared by alkylating p-cyclohexylphenol (I) with iosobutene using Aberlyst A 15 as a catalyst. The raw mixture (II) is esterified with nicotinoyl chloride hydrochloride (III). The product is purified by recristallization from ethanol.
| 【1】 Quack, G.; L44/L44-O. Drugs Fut 1987, 12, 4, 349. |
Extended Information