1-(methoxymethyl)-6b,9a,11b-trimethyl-11-(2-oxopropyl)-7,8,10,11-tetrahydro-1H-furo[4,3,2-de]indeno[4,5-h]isochromene-3,6,9(6bH,9aH,11bH)-trione -Drug Synthesis Database

【结构式】

【分子编号】68043

【品名】1-(methoxymethyl)-6b,9a,11b-trimethyl-11-(2-oxopropyl)-7,8,10,11-tetrahydro-1H-furo[4,3,2-de]indeno[4,5-h]isochromene-3,6,9(6bH,9aH,11bH)-trione

【CA登记号】　

【分子式】C₂₅H₂₈O₇

【分子量】440.493

【元素组成】C 68.17% H 6.41% O 25.43%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(I)

Sonolisib is prepared by condensation of wortmannin (I) with diallylamine (II) in dichloromethane at room temperature .

【1】 Powis, G. (University of Arizona). Wortmannin analogs and methods of using same. CA 2458318, EP 1435941, EP 1686124, EP 1914230, JP 2005507880, WO 2003024183.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	68043	1-(methoxymethyl)-6b,9a,11b-trimethyl-11-(2-oxopropyl)-7,8,10,11-tetrahydro-1H-furo[4,3,2-de]indeno[4,5-h]isochromene-3,6,9(6bH,9aH,11bH)-trione		C₂₅H₂₈O₇	详情	详情
(II)	68044	diallylamine;Di-2-propenylamine;N-2-Propenyl-2-propen-1-amine	124-02-7	C₆H₁₁N	详情	详情

Extended Information