• English
  • 简体中文
Login Register
Current Location: Home > Feedback Help Print

【结 构 式】

【分子编号】67379

【品名】5-methyl-1,3,4-oxadiazole-2-carbonyl chloride

【CA登记号】 

【 分 子 式 】C4H3ClN2O2

【 分 子 量 】146.5328

【元素组成】C 32.79% H 2.06% Cl 24.19% N 19.12% O 21.84%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(X)

 

1 Belyk, K.M., Morrison, H.G., Jones, P., Summa, V. (Merck & Co., Inc.; Istituto di Ricerche di Biologia Molecolare P. Angeletti S.p.A.). Potassium salt of an HIV integrase inhibitor. US 2006122205, WO 2006060712, WO 2006060730.
2 Drugs of the Future 2007, 32(2): 118-122
1 Belyk KM, Morrison HG, Jones P, et al. 2006. Potassium salt of an HIV integrase inhibitor. US 2006/0122205 A1 (Merck & Co Inc).
2 Kassahum K. 2006. Use of atazanavir for improving the pharmacokinetics of drugs metabolized by UGT1A1. WO 2006/060731 A2 (Merck & Co Inc).
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 18029 Acetone cyanohydrin; 2-Hydroxy-2-methylpropanenitrile; 2-Hydroxy-2-methylpropionitrile; 2-Hydroxyisobutyronitrile; 2-Methyllactonitrile; alpha-Hydroxyisobutyronitrile 75-86-5 C4H7NO 详情 详情
(II) 18745 2-amino-2-methylpropanenitrile 19355-69-2 C4H8N2 详情 详情
(III) 67372 benzyl (2-cyanopropan-2-yl)carbamate 100134-82-5 C12H14N2O2 详情 详情
(IV) 67373 (Z)-benzyl (1-amino-1-(hydroxyimino)-2-methylpropan-2-yl)carbamate   C12H17N3O3 详情 详情
(V) 67374 dimethyl 2-((Z)-(1-amino-2-(((benzyloxy)carbonyl)amino)-2-methylpropylidene)amino)maleate   C18H23N3O6 详情 详情
(VI) 67375 methyl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylate   C17H19N3O6 详情 详情
(VII) 67376 methyl 2-(2-(((benzyloxy)carbonyl)amino)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylate 888504-27-6 C18H21N3O6 详情 详情
(VIII) 67377 benzyl (2-(4-((4-fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)carbamate 518048-02-7 C24H25FN4O5 详情 详情
(IX) 67378 2-(2-aminopropan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide 518048-03-8 C16H19FN4O3 详情 详情
(X) 67379 5-methyl-1,3,4-oxadiazole-2-carbonyl chloride   C4H3ClN2O2 详情 详情
Extended Information