4-((2,6-dichloropyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile -Drug Synthesis Database

【结构式】

【分子编号】67127

【品名】4-((2,6-dichloropyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile

【CA登记号】4198-90-7

【分子式】C₁₃H₉Cl₂N₃O

【分子量】294.139

【元素组成】C 53.08% H 3.08% Cl 24.11% N 14.28% O 5.44%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(III)

【1】 Shashikant J, Golak CM, Shyam T, et al. 2010. An improved synthesis of etravirine. Orangic Process Research & Development, 14: 657～660.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	43734	2,4,6-trichloropyrimidine	3764-01-0	C₄HCl₃N₂	详情	详情
(II)	31141	4-Hydroxy-3,5-dimethylbenzonitrile; 2,6-Dimethyl-4-hydroxybenzonitrile	4198-90-7	C₉H₉NO	详情	详情
(III)	67127	4-((2,6-dichloropyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile	4198-90-7	C₁₃H₉Cl₂N₃O	详情	详情
(IV)	15361	4-Aminobenzonitrile	873-74-5	C₇H₆N₂	详情	详情
(V)	67128	4-((4-(4-(aminomethyl)-2,6-dimethylphenoxy)-6-chloropyrimidin-2-yl)amino)benzonitrile		C₂₀H₁₄ClN₅O	详情	详情
(VI)	67129	4-((6-((4-(aminomethyl)phenyl)amino)-2-chloropyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile		C₂₀H₁₄ClN₅O	详情	详情

Extended Information