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【结 构 式】 
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【分子编号】67126 【品名】3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid 【CA登记号】376592-93-7 |
【 分 子 式 】C13H11NO3 【 分 子 量 】229.23528 【元素组成】C 68.11% H 4.84% N 6.11% O 20.94% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(VI)
| 【1】 Duffy KJ, Erickson-Miller CL, Eppley DF, et al.2001. Thrombopoietin mimetics. WO 2001089457 |
| 【2】 Moore S. 2003. Preparation of (pyrazolidenehydrazino) [1,1'-biphenyl]-3-carboxylates as TPO receptor agonists for enhancing platelet prodn. WO 2003098992. |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 67120 | 2-Bromophenol;o-bromophenol | 95-56-7 | C6H5BrO | 详情 | 详情 |
| (II) | 67121 | 2-bromo-6-nitrophenol | 13073-25-1 | C6H4BrNO3 | 详情 | 详情 |
| (III) | 67122 | 1-bromo-2-methoxy-3-nitrobenzene；1-bromo-2-methoxy-3-nitrobenzene | 98775-19-0 | C7H6BrNO3 | 详情 | 详情 |
| (IV) | 67124 | 2'-methoxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid | C14H11NO5 | 详情 | 详情 | |
| (V) | 67125 | 2'-hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid | C13H9NO5 | 详情 | 详情 | |
| (VI) | 67126 | 3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid | 376592-93-7 | C13H11NO3 | 详情 | 详情 |
| (VII) | 67118 | 1-(3,4-dimethylphenyl)-3-methyl-1H-pyrazol-5(4H)-one | 18048-64-1 | C12H14N2O | 详情 | 详情 |
| (VIII) | 67119 | 3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid | 496775-61-2 | C25H22N4O4 | 详情 | 详情 |
| (IX) | 67123 | 3-boronobenzoic acid | C7H7BO4 | 详情 | 详情 |
Extended Information