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【结 构 式】 
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【分子编号】66770 【品名】5-(bromomethyl)-4-hydroxydihydrofuran-2(3H)-one 【CA登记号】 |
【 分 子 式 】C5H7BrO3 【 分 子 量 】195.01278 【元素组成】C 30.8% H 3.62% Br 40.97% O 24.61% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(IV)
| 【1】 Storer R. Moussa A. Wang JY. et al. 2005. Synthesis of β-L-2-deoxy-nucleosides from furanoses and pyranoses via a chloro-sugar and anhydro-l-furanosyl-nucleobase intennediatcs as potential antiviral and antineoplastic agents. W0 2005003374 |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (II) | 66768 | (3S,5S)-3,4-dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one | C5H8O5 | 详情 | 详情 | |
| (VI) | 66772 | 4-hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one | C5H8O4 | 详情 | 详情 | |
| （X） | 12204 | 5-Methyl-2,4(1H,3H)-pyrimidinedione; Thymine | 65-71-4 | C5H6N2O2 | 详情 | 详情 |
| (I) | 66767 | (3S,4R,5S)tetrahydro-2H-pyran-2,3,4,5-tetrol | C5H10O5 | 详情 | 详情 | |
| (III) | 66769 | 3-bromo-5-(bromomethyl)-4-hydroxydihydrofuran-2(3H)-one | C5H6Br2O3 | 详情 | 详情 | |
| (IV) | 66770 | 5-(bromomethyl)-4-hydroxydihydrofuran-2(3H)-one | C5H7BrO3 | 详情 | 详情 | |
| (V) | 66771 | potassium 3-hydroxy-3-(oxiran-2-yl)propanoate | C5H7KO4 | 详情 | 详情 | |
| (VII) | 66773 | C21H21O6 | 详情 | 详情 | ||
| (VIII) | 62916 | {(2S,3R)-5-hydroxy-3-[(4-methylbenzoyl)oxy]tetrahydro-2-furanyl}methyl 4-methylbenzoate | C21H22O6 | 详情 | 详情 | |
| (IX) | 37194 | (2R,3S)-5-Chloro-2-[[(4-methylbenzoyl)oxy]methyl]tetrahydro-3-furanyl 4-methylbenzoate | 4330-21-6 | C21H21ClO5 | 详情 | 详情 |
| (XI) | 12238 | 5-Methyl-1,3-bis(trimethylsilyl)-2,4(1H,3H)-pyrimidinedione | 3444-09-5 | C11H22N2O2Si2 | 详情 | 详情 |
| (XII) | 62918 | {(2S,3R,5S)-3-[(4-methylbenzoyl)oxy]-5-[5-methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl]tetrahydro-2-furanyl}methyl 4-methylbenzoate | C26H26N2O7 | 详情 | 详情 |
Extended Information