N-(5-(bromomethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide -Drug Synthesis Database

【结构式】

【分子编号】66687

【品名】N-(5-(bromomethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

【CA登记号】　

【分子式】C₁₆H₁₉BrFN₃O₂S

【分子量】416.314

【元素组成】C 46.16% H 4.60% Br 19.19% F 4.56% N 10.09% O 7.69% S 7.70%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(I)

【1】 Mei GY．Cai QF. 2005．Preparation for rosurrastatin and its intermediates. 发明专利申请公开说明书，CN 1687087(本专利属于Zhqiang HiSIm Pharmaceutical Co，Ltd，Peop Rep China)

中间体序号	中间体编号	品名	分子式	供应商	用于合成
(I)	66687	N-(5-(bromomethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide	C₁₆H₁₉BrFN₃O₂S	详情	详情
(II)	66688	((4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)methyl)triphenylphosphonium	C₃₄H₃₄FN₃O₂PS	详情	详情
(III)	66689	tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate	C₁₃H₂₂O₅	详情	详情
(IV)	66682	tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate	C₂₉H₄₀FN₃O₆S	详情	详情

Extended Information