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【结 构 式】

【分子编号】66678

【品名】(3R,5S,E)-(R)-2-(benzyloxy)-2-oxo-1-phenylethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate

【CA登记号】 

【 分 子 式 】C37H40FN3O8S

【 分 子 量 】705.804

【元素组成】C 62.96% H 5.71% F 2.69% N 5.95% O 18.13% S 4.54%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(III)

 

1 Zhao ZQ,Peng LZ 2006.Preparation of Rosuvastatin and its salt. 发明专利申请公开说明书,CN(本专利属于Lunan Pharmaceutical Group Co,Ltd.Peop Rep China)
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 66676 (R,E)-(R)-2-(benzyloxy)-2-oxo-1-phenylethyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-oxohept-6-enoate   C43H52FN3O8SSi 详情 详情
(II) 66677 (3R,5S,E)-(R)-2-(benzyloxy)-2-oxo-1-phenylethyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxyhept-6-enoate   C43H54FN3O8SSi 详情 详情
(III) 66678 (3R,5S,E)-(R)-2-(benzyloxy)-2-oxo-1-phenylethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate   C37H40FN3O8S 详情 详情
(IV) 66679 (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid   C22H28FN3O6S 详情 详情
Extended Information