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【结 构 式】 
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【分子编号】66677 【品名】(3R,5S,E)-(R)-2-(benzyloxy)-2-oxo-1-phenylethyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxyhept-6-enoate 【CA登记号】 |
【 分 子 式 】C43H54FN3O8SSi 【 分 子 量 】820.067 【元素组成】C 62.98% H 6.64% F 2.32% N 5.12% O 15.61% S 3.91% Si 3.42% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)
| 【1】 Zhao ZQ，Peng LZ 2006．Preparation of Rosuvastatin and its salt. 发明专利申请公开说明书，CN(本专利属于Lunan Pharmaceutical Group Co，Ltd．Peop Rep China) |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 66676 | (R,E)-(R)-2-(benzyloxy)-2-oxo-1-phenylethyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-oxohept-6-enoate | C43H52FN3O8SSi | 详情 | 详情 | |
| (II) | 66677 | (3R,5S,E)-(R)-2-(benzyloxy)-2-oxo-1-phenylethyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxyhept-6-enoate | C43H54FN3O8SSi | 详情 | 详情 | |
| (III) | 66678 | (3R,5S,E)-(R)-2-(benzyloxy)-2-oxo-1-phenylethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate | C37H40FN3O8S | 详情 | 详情 | |
| (IV) | 66679 | (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid | C22H28FN3O6S | 详情 | 详情 |
Extended Information