dimethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-propyl-1H-imidazole-4,5-dicarboxylate -Drug Synthesis Database

【结构式】

【分子编号】66556

【品名】dimethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-propyl-1H-imidazole-4,5-dicarboxylate

【CA登记号】　

【分子式】C₂₄H₂₄N₆O₄

【分子量】460.493

【元素组成】C 62.60% H 5.25% N 18.25% O 13.90%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(IV)

【1】 Sebastian S,Gade SR, Mallepalli SR, et aL 2007. Process for preparation of olmesartan medoxomiL. W0 2007047838．(本专利属于Dr Reddy's Laboratories Ltd, India; Dr Reddy's Laboratories, Inc)

中间体序号	中间体编号	品名	分子式	供应商	用于合成
(I)	16905	2-propyl-1H-imidazole-4,5-dicarboxylic acid	C₈H₁₀N₂O₄	详情	详情
(II)	16906	diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate	C₁₂H₁₈N₂O₄	详情	详情
(III)	66559	5-(4'-(bromomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole	C₁₄H₁₁BrN₄	详情	详情
(IV)	66556	dimethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-propyl-1H-imidazole-4,5-dicarboxylate	C₂₄H₂₄N₆O₄	详情	详情
(V)	16920	ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-1,2,3,4-tetraazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylate	C₂₆H₃₀N₆O₃	详情	详情
(VI)	16910	4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1-trityl-1H-1,2,3,4-tetraazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid	C₄₃H₄₀N₆O₃	详情	详情
(VII)	16911	4-(chloromethyl)-5-methyl-1,3-dioxol-2-one	C₅H₅ClO₃	详情	详情

Extended Information