【结 构 式】 |
【分子编号】66559 【品名】5-(4'-(bromomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole 【CA登记号】 |
【 分 子 式 】C14H11BrN4 【 分 子 量 】315.1723 【元素组成】C 53.35% H 3.52% Br 25.35% N 17.78% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号:(III)
【1】 Sebastian S,Gade SR, Mallepalli SR, et aL 2007. Process for preparation of olmesartan medoxomiL. W0 2007047838.(本专利属于Dr Reddy's Laboratories Ltd, India; Dr Reddy's Laboratories, Inc) |
中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
---|---|---|---|---|---|---|
(I) | 16905 | 2-propyl-1H-imidazole-4,5-dicarboxylic acid | C8H10N2O4 | 详情 | 详情 | |
(II) | 16906 | diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate | C12H18N2O4 | 详情 | 详情 | |
(III) | 66559 | 5-(4'-(bromomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole | C14H11BrN4 | 详情 | 详情 | |
(IV) | 66556 | dimethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-propyl-1H-imidazole-4,5-dicarboxylate | C24H24N6O4 | 详情 | 详情 | |
(V) | 16920 | ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-1,2,3,4-tetraazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylate | C26H30N6O3 | 详情 | 详情 | |
(VI) | 16910 | 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1-trityl-1H-1,2,3,4-tetraazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid | C43H40N6O3 | 详情 | 详情 | |
(VII) | 16911 | 4-(chloromethyl)-5-methyl-1,3-dioxol-2-one | C5H5ClO3 | 详情 | 详情 |
Extended Information