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【结 构 式】 
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【分子编号】61880 【品名】1-hexadecene 【CA登记号】 |
【 分 子 式 】C16H32 【 分 子 量 】224.43008 【元素组成】C 85.63% H 14.37% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(I)In a related procedure, halogenation of 1-hexadecene (I) with N-bromosuccinimide in THF/H2O leads to a mixture of regioisomeric bromohydrins (II) and (III). Refluxing of this mixture of bromohydrins with N,N-dimethyl ethanolamine (IV) in MeOH gives rise to the title ammonium salt as the only isomer.
| 【1】 Wong, Y.-L.; et al.; Spermicidal, anti-HIV, and micellar properties of di- and trihydroxylated cationic surfactants. Tetrahedron 2002, 58, 1, 45. |
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