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【结 构 式】 
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【分子编号】56971 【品名】O-Acetylsyringaldehyde; 4-Acetoxy-3,5-dimethoxybenzaldehyde 【CA登记号】53669-33-3 |
【 分 子 式 】C11H12O5 【 分 子 量 】224.21328 【元素组成】C 58.93% H 5.39% O 35.68% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(IV)Deoxyvascinone (III) is prepared from o-azidobenzoyl chloride (I) and 2-pyrrolidinone (II) following a reported procedure. Then, Claisen-Schmidt condensation between deoxyvascinone (III) and 4-acetoxy-3,5-dimethoxybenzaldehyde (IV) in boiling acetic anhydride leads to the title compound.
| 【1】 Molina, P.; et al.; Inhibition of leukocyte functions by the alkaloid isaindigotone from Isatis indigotica and some new synthetic derivatives. J Nat Prod 2001, 64, 10, 1297. |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 56969 | 2-azidobenzoyl chloride | C7H4ClN3O | 详情 | 详情 | |
| (II) | 27397 | 2-Pyrrolidinone | 616-45-5 | C4H7NO | 详情 | 详情 |
| (III) | 56970 | 2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one | C11H10N2O | 详情 | 详情 | |
| (IV) | 56971 | O-Acetylsyringaldehyde; 4-Acetoxy-3,5-dimethoxybenzaldehyde | 53669-33-3 | C11H12O5 | 详情 | 详情 |
Extended Information