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【结 构 式】 
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【分子编号】56039 【品名】2-{2-[(E)-2-(1-methylethylidene)hydrazono]-4-oxo-1,3-thiazolidin-5-yl}acetic acid 【CA登记号】 |
【 分 子 式 】C8H11N3O3S 【 分 子 量 】229.25976 【元素组成】C 41.91% H 4.84% N 18.33% O 20.94% S 13.99% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(I)The title amide was prepared by coupling of the previously reported 5-carboxymethyl-2-isopropylidenehydrazonothiazolidin-4-one (I) with aniline (II) in the presence of EDC and HOBt.
| 【1】 Yasumura, K.; Miyajima, K.; Nagahama, T.; Ishikawa, S.; Tohyama, Y.; Sugiyama, K. (Otsuka Pharmaceutical Co., Ltd.); Thiazole or imidazole derivs. as Maillard reaction inhibitors. EP 0638075; JP 1995133264; JP 1998167965; WO 9419335 . |
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