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【结 构 式】 
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【分子编号】66123 【品名】1,1,3,3-tetramethyl-2-(2-oxopiperidin-1-yl)isouronium tetrafluoroborate 【CA登记号】 |
【 分 子 式 】C10H20F4N3O2 【 分 子 量 】290.281 【元素组成】C 41.38% H 6.94% F 26.18% N 14.48% O 11.02% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(XXII)
| 【1】 Fassler A, Bold G, Capraro H, et aL 1996. Aza-peptide analogs as potent human immunodeficiency virus type-l protease inhibitors with oral bioavailability.JMed Cha;n, 39, 3203一3216 |
| 【2】 Fassler A, Bold G, Capraro H, et aL 1997. lruermediates Ior the prepantion of peptide analogues, W0 9746514 |
| 【3】 Giordano C, Pozzoli C, Benedetti F.2001. Ptocess for the pr帕嘣tion可8ryl-pyritlinyl compounds, W0 012083 |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 22231 | 4-Bromobenzaldehyde | 1122-91-4 | C7H5BrO | 详情 | 详情 |
| (II) | 23438 | (4-bromophenyl)(methoxy)methyl methyl ether; 1-bromo-4-(dimethoxymethyl)benzene | C9H11BrO2 | 详情 | 详情 | |
| (III) | 29052 | 2-Bromopyridine；α-bromopyridine;α-bromoazine | 109-04-6 | C5H4BrN | 详情 | 详情 |
| (IV) | 23440 | 4-(2-pyridinyl)benzaldehyde | C12H9NO | 详情 | 详情 | |
| (V) | 10893 | tert-butyl 1-hydrazinecarboxylate; tert-butyl carbazate | 870-46-2 | C5H12N2O2 | 详情 | 详情 |
| (VI) | 23442 | tert-butyl 2-[(Z)-[4-(2-pyridinyl)phenyl]methylidene]-1-hydrazinecarboxylate | C17H19N3O2 | 详情 | 详情 | |
| (VII) | 23452 | tert-butyl (1S)-1-benzyl-2-oxoethylcarbamate | C14H19NO3 | 详情 | 详情 | |
| (VIII) | 23444 | tert-butyl (1S)-1-[(2R)oxiranyl]-2-phenylethylcarbamate | C15H21NO3 | 详情 | 详情 | |
| (XXI) | 66122 | (2R,3R)-3-amino-4-phenyl-1-(1-(4-(pyridin-2-yl)benzyl)hydrazinyl)butan-2-ol trihydrochloride | C22H29Cl3N4O | 详情 | 详情 | |
| (XXII) | 66123 | 1,1,3,3-tetramethyl-2-(2-oxopiperidin-1-yl)isouronium tetrafluoroborate | C10H20F4N3O2 | 详情 | 详情 |
Extended Information