|
【结 构 式】 
|
【分子编号】48057 【品名】4-cyano-N-(4-cyanophenyl)benzamide 【CA登记号】 |
【 分 子 式 】C15H9N3O 【 分 子 量 】247.25608 【元素组成】C 72.87% H 3.67% N 16.99% O 6.47% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(III)Coupling between 4-cyanobenzoyl chloride (I) and 4-aminobenzonitrile (II) in the presence of Et3N afforded the corresponding amide (III). The dicyano compound (III) was then treated with sodium azide and ammonium chloride in hot DMF to produce the title bis-tetrazolyl derivative.
| 【1】 Makovec, F.; Peris, W.; Rovati, A.L. (Rotta Research Laboratorium SpA); Derivs. of N-phenylbenzamide with anti-ulcer and anti-allergy activity and a method for their preparation. EP 0460083; JP 1992503514; US 5232937; WO 9009989 . |
Extended Information