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【结 构 式】 
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【分子编号】47305 【品名】5-amino-4-oxopentanoic acid 【CA登记号】106-60-5 |
【 分 子 式 】C5H9NO3 【 分 子 量 】131.1314 【元素组成】C 45.8% H 6.92% N 10.68% O 36.6% |
与该中间体有关的原料药合成路线共 2 条
合成路线1
该中间体在本合成路线中的序号：(I)The desired product can be easily obtained by formation of the methyl ester of the commercially available 5-amino-levulinic acid hydrochloride (I) by heating in MeOH in the presence of HCl.
| 【1】 Moan, J.; Steen, H.; Gierskcky, K.E.; Warloe, T.; Bjorseth, A.; Peng, Q. (PhotoCure ASA); Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy. US 6034267; WO 9628412 . |
合成路线2
该中间体在本合成路线中的序号：(I)
| 【1】 Lorena R, Gabriela DV, Adrianna C, et al. 2009. Porphyrin synthesis from amminolevulinic acid esters in endothelial and its role in photodynamic therapy. Journal of Photochemistry and Photobiology B: Biology, 96: 249～254. |
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