2-[(E)-1-amino-2-cyano-2-nitroethenyl]-1-hydrazinecarboximidamide -Drug Synthesis Database

【结构式】

【分子编号】46030

【品名】2-[(E)-1-amino-2-cyano-2-nitroethenyl]-1-hydrazinecarboximidamide

【CA登记号】

【分子式】C₄H₇N₇O₂

【分子量】185.14556

【元素组成】C 25.95% H 3.81% N 52.96% O 17.28%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(III)

The condensation of nitroenamine (I) with aminoguanidine (II) afforded compound (III), which was subsequently cyclized to the title pyrazole by treatment with NaOH.

参考文献中间体

合成目标

【1】 Makarov, V.; et al.; 4-Nitropyrazole derivatives as new exogenic donors of nitric oxide. 16th Int Symp Med Chem (Sept 18 2000, Bologna) 2000, Abst PA-120.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	46029	(E)-3-amino-3-(dimethylamino)-2-nitro-2-propenenitrile		C₅H₈N₄O₂	详情	详情
(II)	10015	1-Hydrazinecarboximidamide; Hydrazinecarboximidamide	79-17-4	CH₆N₄	详情	详情
(III)	46030	2-[(E)-1-amino-2-cyano-2-nitroethenyl]-1-hydrazinecarboximidamide		C₄H₇N₇O₂	详情	详情

Extended Information