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【结 构 式】 
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【药物名称】 【化学名称】3,5-Diamino-4-nitro-1H-pyrazole-1-carboxamidine 【CA登记号】 【 分 子 式 】C4H7N7O2 【 分 子 量 】185.14609 |
【开发单位】Friedrich-Schiller-Universität Jena (Originator), NIOPIK (Originator) 【药理作用】CARDIOVASCULAR DRUGS, Hypertension, Treatment of, Nitric Oxide Donors |
合成路线1
The condensation of nitroenamine (I) with aminoguanidine (II) afforded compound (III), which was subsequently cyclized to the title pyrazole by treatment with NaOH.
| 【1】 Makarov, V.; et al.; 4-Nitropyrazole derivatives as new exogenic donors of nitric oxide. 16th Int Symp Med Chem (Sept 18 2000, Bologna) 2000, Abst PA-120. |
Extended Information