platinum(2+) chloride iodide cyclopentanamine ammoniate -Drug Synthesis Database

【结构式】

【分子编号】50818

【品名】platinum(2+) chloride iodide cyclopentanamine ammoniate

【CA登记号】

【分子式】C₅H₁₄ClIN₂Pt

【分子量】459.61681

【元素组成】C 13.07% H 3.07% Cl 7.71% I 27.61% N 6.09% Pt 42.44%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(II)

Treatment of cyclopentylamine (I) with potassium trichloroaminoplatinate and potassium iodide in H2O provides a mixture of platinum complexes (II) and (III), which is then subjected to reaction with silver (S)-(-)-malate (IV) in H2O to furnish the desired platinum complex.

参考文献中间体

合成目标

【1】 Cheltsov-Bebutov, P.A.; Kravchenko, A.N.; Schelokov, R.N.; Konovalova, A.L.; Presnov, M.A.; Ivanov, V.B. (Inst. Obs. Neorg. Khim. Imeni; Vse. Onkol. Nauch. Tsentr Ak.); Carboxylatoplatinum(II) complexes and process for their preparation. FR 2563524 .

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	28850	cyclopentanamine	1003-03-8	C₅H₁₁N	详情	详情
(II)	50818	platinum(2+) chloride iodide cyclopentanamine ammoniate		C₅H₁₄ClIN₂Pt	详情	详情
(III)	50820			C₅H₁₄I₂N₂Pt	详情	详情
(IV)	50819			C₄H₄AgO₅	详情	详情

Extended Information