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【结 构 式】 
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【分子编号】42285 【品名】(3aS,6aR,9aR,9bR)-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one 【CA登记号】 |
【 分 子 式 】C15H18O2 【 分 子 量 】230.30672 【元素组成】C 78.23% H 7.88% O 13.89% |
与该中间体有关的原料药合成路线共 2 条
合成路线1
该中间体在本合成路线中的序号：(I)By condensation of dehydrocostus lactone (I) (isolated from the dried roots of Chinese plant Saussurea lappa) with L-proline (II) by means of Et3N in refluxing ethanol.
| 【1】 Matsuda, H.; et al.; Absolute stereostructures and syntheses of saussureamines A, B, C, D and E, amino acid-sesquiterpene conjugates with gastroprotective effect, from the roots of Saussurea lappa. Tetrahedron 2000, 56, 39, 7763. |
合成路线2
该中间体在本合成路线中的序号：(I)By condensation of dehydrocostus lactone (I) (isolated from the dried roots of Chinese plant Saussurea lappa) with L-asparagine (II) by means of Et3N in refluxing ethanol.
| 【1】 Matsuda, H.; et al.; Absolute stereostructures and syntheses of saussureamines A, B, C, D and E, amino acid-sesquiterpene conjugates with gastroprotective effect, from the roots of Saussurea lappa. Tetrahedron 2000, 56, 39, 7763. |
Extended Information