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【结 构 式】 
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【分子编号】40706 【品名】 【CA登记号】 |
【 分 子 式 】C6H14Cl2N4O6Pt 【 分 子 量 】504.18592 【元素组成】C 14.29% H 2.8% Cl 14.06% N 11.11% O 19.04% Pt 38.69% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(III)Dichlorocyclohexane-1,2-diamine platinum complex (II) was prepared from (R,R)-1,2-cyclohexanediamine (I) according to a known method. Subsequent treatment of (II) with aqueous silver nitrate produced the diaqua complex (III). Finally, displacement of H2O by means of sodium myristate (IV) gave rise to the title compound.
| 【1】 Maeda, M.; Sasaki, T. (Sumitomo Pharmaceuticals Co., Ltd.); Liposoluble platinum (II) complex and preparation thereof. AU 8654358; EP 0193936; JP 1987000096 . |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 11130 | (1R,2R)-1,2-cyclohexanediamine; (1R,2R)-2-aminocyclohexylamine; cis-1,2-Diaminocyclohexane | 20439-47-8 | C6H14N2 | 详情 | 详情 |
| (II) | 23063 | (R,R)-Cyclohexane-1,2-diamine dichloro platinum complex | C6H14Cl2N2Pt | 详情 | 详情 | |
| (III) | 40706 | C6H14Cl2N4O6Pt | 详情 | 详情 | ||
| (IV) | 40707 | sodium myristate | 822-12-8 | C14H27NaO2 | 详情 | 详情 |
Extended Information