【结 构 式】 ![]() |
【分子编号】39227 【品名】 【CA登记号】 |
【 分 子 式 】C12H21NO6 【 分 子 量 】275.30188 【元素组成】C 52.35% H 7.69% N 5.09% O 34.87% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号:(II)4-(tert-Butoxycarbonylamino)butyric acid (I) was activated as the corresponding mixed anhydride (II) by treatment with ethyl chloroformate and triethylamine. Subsequent coupling of (II) with 4-aminopyridine (III) afforded the title amide.
【1】 Leoni, A.; Villetti, G.; Morigi, R.; Pietra, C.; Andreani, A.; Locatelli, A.; Rambaldi, M.; 4-Aminopyridine derivatives with antiamnesic activity. Eur J Med Chem 2000, 35, 1, 77. |
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