|
【结 构 式】 
|
【药物名称】 【化学名称】N-[4-Oxo-4-(4-pyridinylamino)butyl]carbamic acid tert-butyl ester 【CA登记号】266353-29-1 【 分 子 式 】C14H21N3O3 【 分 子 量 】279.34177 |
【开发单位】Chiesi (Originator) 【药理作用】Cognition Disorders, Treatment of, NEUROLOGIC DRUGS |
合成路线1
4-(tert-Butoxycarbonylamino)butyric acid (I) was activated as the corresponding mixed anhydride (II) by treatment with ethyl chloroformate and triethylamine. Subsequent coupling of (II) with 4-aminopyridine (III) afforded the title amide.
| 【1】 Leoni, A.; Villetti, G.; Morigi, R.; Pietra, C.; Andreani, A.; Locatelli, A.; Rambaldi, M.; 4-Aminopyridine derivatives with antiamnesic activity. Eur J Med Chem 2000, 35, 1, 77. |
Extended Information