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【结 构 式】 
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【分子编号】36166 【品名】2-bromo-1-(2-naphthyl)-1-ethanone 【CA登记号】613-54-7 |
【 分 子 式 】C12H9BrO 【 分 子 量 】249.10686 【元素组成】C 57.86% H 3.64% Br 32.08% O 6.42% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(I)By reaction of 2-naphthyl bromomethyl ketone (I) with imidazole (II) in DMF, followed by a treatment with HCl in ether.
| 【1】 Walker, K.A.M.; GB 1540023 . |
| 【2】 Hirschfeld, D.R.; Walker, K.A.M.; Wallach, M.B.; 1-(Naphthylalyl)-1H-imidazole derivatives, a new class of anticonvulsant agents. J Med Chem 1981, 24, 1, 67. |
| 【3】 Walker, K.A.M. (Syntex (USA), Inc.); 1-(Naphthylethyl)imidazole derivs., their preparation, and pharmaceutical compsns. containing them. EP 0001926 . |
| 【4】 Walker, K.A.M. (Syntex (USA), Inc.); Imidazole derivs., their preparation and their use in pharmaceutical compsns.. EP 0013786 . |
| 【5】 Serradell, M.N.; Blancafort, P.; Castaner, J.; Nafimidone hydrochloride. Drugs Fut 1983, 8, 8, 689. |
Extended Information