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【结 构 式】

【分子编号】36151

【品名】1,3,3,5,5-pentachloro-1lambda(6),2,4,6,3lambda(5),5lambda(5)-thiatriazadiphosphinin-1-one

【CA登记号】

【 分 子 式 】Cl5N3OP2S

【 分 子 量 】329.296644

【元素组成】Cl 53.83% N 12.76% O 4.86% P 18.81% S 9.74%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(I)

By reaction of 1,3,3,5,5-pentachloro-1-thia-2,4,6-triaza-3,5-diphosphorine-1-oxide (I) with aziridine (II) in ether.

1 Van der Huizen, A.A.; Sournies, F.; Labarre, J.F.; Van der Grampel, J.C.; Wiedijk, D.; Jekel, A.P.; Derivatives of cis-NPCl2(NSOCl)2 and (NPCl2)2 NSOCl. Part XVI. The preparation of some aziridino (ethyleneimino) derivatives of (NPCl2)2 NSOX (X=F,Az,Ph) with a potential anticancer activity. Inorg Chim Acta 1981, 53, 4, 169-170.
2 Labarre, J.F.; Sournies, F.; Van der Grampel, J.; Van der Huizen, A. (ANVAR (Agence Natl. Valor. Rech.)); Inorganocyclic cpds. usable as medicaments and a process for their preparation. EP 0022407 .
3 Blancafort, P.; Castaner, J.; Serradell, M.N.; Hopkins, S.J.; SOAz. Drugs Fut 1983, 8, 7, 605.
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 36151 1,3,3,5,5-pentachloro-1lambda(6),2,4,6,3lambda(5),5lambda(5)-thiatriazadiphosphinin-1-one Cl5N3OP2S 详情 详情
(II) 10151 Ethyleneimine; Aziridine; Azirane 151-56-4 C2H5N 详情 详情
Extended Information