【结 构 式】 |
【分子编号】34752 【品名】carbonothioic dihydrazide 【CA登记号】2231-57-4 |
【 分 子 式 】CH6N4S 【 分 子 量 】106.1516 【元素组成】C 11.31% H 5.7% N 52.78% S 30.21% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号:(II)The condensation between pyruvic acid (I) and thiocarbohydrazide (II) provided 4-amino-3-mercapto-6-methyl-1,2,4-triazin-5(4H)-one (III). Further ring closure of (III) with (4-methylphenoxy)acetic acid (IV) by means of POCl3 yielded the required thiadiazolo triazinone.
【1】 Shridhara, K.; Sarojini, B.K.; Holla, B.S.; Antony, G.; Synthesis of some new biologically active thiadiazolotriazinones - Part II. Farmaco 1999, 54, 3, 149. |
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