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【结 构 式】 
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【分子编号】33310 【品名】benzoylhydrazine; benzhydrazide; benzohydrazide 【CA登记号】613-94-5 |
【 分 子 式 】C7H8N2O 【 分 子 量 】136.1534 【元素组成】C 61.75% H 5.92% N 20.57% O 11.75% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)By condensation of daunorubicin-HCl (I) with benzoylhydrazine (II) by means of acetic acid in ethanol at 60 C.
| 【1】 Jolles, G.; Neue Naphthacenderivate und ihre Herstellung. DE 2327211 . |
| 【2】 Castaner, J.; Woodman, R.J.; Zorubicin. Drugs Fut 1979, 4, 1, 61. |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 18698 | 7-(3-Amino-2,3,6-trideoxy-L-lyxo-hexosyloxy)-9-acetyl-7,8,9,10-tetrahydro-6,9,11-trihydroxy-4-methoxy-5,12-naphthacenequinone; (8S,10S)-8-acetyl-10-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy]-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydro-5,12-naphthacenedione; (1S,3S)-3-Acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-alpha-lyxo-hexopyranoside; Daunomycin | 20830-81-3 | C27H29NO10 | 详情 | 详情 |
| (II) | 33310 | benzoylhydrazine; benzhydrazide; benzohydrazide | 613-94-5 | C7H8N2O | 详情 | 详情 |
Extended Information