(7R,8R,9S,13S,14S)-7,13-dimethyl-3,17-dioxo-1,2,3,6,7,8,9,11,12,13,14,15,16,17-tetradecahydro-10H-cyclopenta[a]phenanthrene-10-carbaldehyde -Drug Synthesis Database

【结构式】

【分子编号】32184

【品名】(7R,8R,9S,13S,14S)-7,13-dimethyl-3,17-dioxo-1,2,3,6,7,8,9,11,12,13,14,15,16,17-tetradecahydro-10H-cyclopenta[a]phenanthrene-10-carbaldehyde

【CA登记号】

【分子式】C₂₀H₂₆O₃

【分子量】314.42464

【元素组成】C 76.4% H 8.33% O 15.27%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(I)

By condensation of 7-methyl-3,17,19-trioxo-DELTA4-androstene (I) with acetylene by means of potassium in liquid ammonia.

【1】 Solomon, M.; Harryvan, E.A.; Process for the preparation of delta[5,(10)]-3-keto-19-nor-steroids. BE 0700390; DE 1618747; FR 1527563; GB 1177845; US 3475465 .
【2】 Castaner, J.; Serradell, M.N.; Blancafort, P.; Hillier, K.; Tibolone. Drugs Fut 1981, 6, 5, 302.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
	23634	acetylene	74-86-2	C₂H₂	详情	详情
(I)	32184	(7R,8R,9S,13S,14S)-7,13-dimethyl-3,17-dioxo-1,2,3,6,7,8,9,11,12,13,14,15,16,17-tetradecahydro-10H-cyclopenta[a]phenanthrene-10-carbaldehyde		C₂₀H₂₆O₃	详情	详情

Extended Information