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【结 构 式】 
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【分子编号】31974 【品名】1-propene 【CA登记号】115-07-1 |
【 分 子 式 】C3H6 【 分 子 量 】42.08064 【元素组成】C 85.63% H 14.37% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)By condensation of phenol (I) with propylene (II) at temperatures ranging from 230 C to 275 C and pressures up to 3000 atm. in an autoclave, using aluminum phenoxide as catalyst.
| 【1】 Napolitano, J.P.; Ecke, G.G.; Kolka, A.J.; The ortho-alkylation of phenols. J Org Chem 1956, 21, 712-713. |
| 【2】 Kealy, T.J.; Coffman, D.D.; Thermal addition reactions of monocyclic phenols with ethylene. J Org Chem 1961, 26, 987-992. |
| 【3】 Ecke, G.G.; Kolka, A.J.; Napolitano, J.P.; Filbey, A.H.; The ortho-alkylation of phenols. J Org Chem 1957, 22, 642-646. |
| 【4】 Serradell, M.N.; Castaner, J.; Sneddon, J.M.; Blancafort, P.; Disoprofol. Drugs Fut 1982, 7, 3, 156. |
Extended Information