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【结 构 式】 
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【分子编号】31710 【品名】[1,1'-biphenyl]-4-yl(phenyl)methanol 【CA登记号】 |
【 分 子 式 】C19H16O 【 分 子 量 】260.33544 【元素组成】C 87.66% H 6.19% O 6.15% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)The reduction of 4-phenylbenzophenone (I) with NaBH4 in ethanol gives 4-phenylbenzhydrol (II), which is then condensed with imidazole (III) by means of SOCl2 in acetonitrile.
| 【1】 Regel, E.; Draber, W.; Buechel, K.H.; Plempel, M. (Bayer AG); alpha-(4-Biphenylyl)-benzylazolium salts and their use for combating microorganisms. BE 0859041; DE 2643563; FR 2365559; GB 1535148; JP 53044568; NL 7710489; US 4243670 . |
| 【2】 Regel, E.; Draber, W.; Buechel, K.H.; Plempel, M. (Bayer AG); Substituted azol-1-ylmethanes. BE 0836924; CA 1059134; CH 619454; DD 124729; DE 2461406; FR 2295747; GB 1469617; JP 51091260; NL 7514940; US 4118487 . |
| 【3】 Regel, E.; Draber, W.; Buechel, K.H.; Plempel, M. (Bayer AG); Combating crop damaging fungi with alpha-(4-biphenylyl)-benzyl-azolium salts. DE 2714290; JP 53121941; US 4251540 . |
| 【4】 Serradell, M.N.; Blancafort, P.; Castaner, J.; Bifonazole. Drugs Fut 1982, 7, 2, 87. |
Extended Information