2-ethylhexylamine; 2-ethyl-1-hexanamine -Drug Synthesis Database

【结构式】

【分子编号】31410

【品名】2-ethylhexylamine; 2-ethyl-1-hexanamine

【CA登记号】104-75-6

【分子式】C₈H₁₉N

【分子量】129.2456

【元素组成】C 74.35% H 14.82% N 10.84%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(II)

The reaction of diketene (I) with 2-ethylhexylamine (II) gives N-(2-ethylhexyl)acetoacetamide (III), which is reduced to the target compound with H2 over Raney-Ni in methanol.

参考文献中间体

合成目标

【1】 Yamagisawa, I.; Torii, S.; Sakuma, A. (Lion Corp.); N-Substd.-beta-oxybutyramide semisuccinate and its salt having effects of increasing paradoxical sleep and tranquillizing. DE 1768445; US 3639457 .

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	11367	4-Methylene-2-oxetanone; Acetyl ketene	674-82-8	C₄H₄O₂	详情	详情
(II)	31410	2-ethylhexylamine; 2-ethyl-1-hexanamine	104-75-6	C₈H₁₉N	详情	详情
(III)	31411	N-(2-ethylhexyl)-3-oxobutanamide	32837-36-8	C₁₂H₂₃NO₂	详情	详情

Extended Information