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【结 构 式】

【分子编号】30567

【品名】4-[[(2-carboxyethyl)amino]carbonyl]benzenediazonium chloride

【CA登记号】

【 分 子 式 】C10H10ClN3O3

【 分 子 量 】255.66052

【元素组成】C 46.98% H 3.94% Cl 13.87% N 16.44% O 18.77%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(II)

The diazotation of 3-(4-aminobenzoylamino)propionic acid (I) with NaNO2 and HCl gives the corresponding diazonium salt (II), which is then condensed with salicylic acid.

1 Chan, R.P.K. (Biorex Laboratories Ltd.); 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith. GB 2080796 .
2 Serradell, M.N.; Castaner, J.; Balsalazide and Ipsalazide. Drugs Fut 1984, 9, 5, 313.
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 30566 N-(4-aminobenzoyl)-beta-alanine 7377-08-4 C10H12N2O3 详情 详情
(II) 30567 4-[[(2-carboxyethyl)amino]carbonyl]benzenediazonium chloride C10H10ClN3O3 详情 详情
(III) 15240 2-Hydroxybenzoic acid; Salicylic acid 69-72-7 C7H6O3 详情 详情
Extended Information