|
【结 构 式】 
|
【分子编号】28072 【品名】5-[benzyl(tert-butoxycarbonyl)amino]pentyl 4-methylbenzenesulfonate 【CA登记号】 |
【 分 子 式 】C24H33NO5S 【 分 子 量 】447.59576 【元素组成】C 64.4% H 7.43% N 3.13% O 17.87% S 7.16% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)The title compound was obtained by alkylation of tetraazacyclo tetradecane (I) with an excess of tosylate (II) in the presence of K2CO3 in refluxing acetonitrile.
| 【1】 Trabaud, C.; Dessolin, J.; Camplo, M.; Hantz, O.; Zoulim, F.; Borel, C.; Meyer, M.; Pepe, G.; Chermann, J.-C.; Kraus, J.-L.; Design, synthesis and structure relationships of new N,N',N'',N'''-tetrakis (omega-amino alkyl) tetraazamacrocycles. Antivir Chem Chemother 1998, 9, 1, 73-84. |
| 【2】 Chermann, J.C.; Dessolin, J.; Bouygues, M.; Trabaud, C.; Kraus, J.L.; Vieghe, P.; Camplo, M.; Modelisation, synthesis and anti-HIV activities of N,N,N',N'',N'''-pentakistetraazamacrocycles salts derivatives. Bioorg Med Chem Lett 1997, 7, 10, 1353. |
Extended Information