【结 构 式】 |
【分子编号】27376 【品名】1,10-dichlorodecane 【CA登记号】2162-98-3 |
【 分 子 式 】C10H20Cl2 【 分 子 量 】211.1742 【元素组成】C 56.88% H 9.55% Cl 33.58% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号:(IV)The condensation of octylamine (I) with 4-bromopyridine by heating at 180 C gives (4-octylamino)piridine (III), which is then allowed to react with 1,10-dichlorodecane by heating 120-80 C.
【1】 Bailey, D.M.; et al.; Bispyridinamines: A new class of topical antimicrobial agents as inhibitors of dental plaque. J Med Chem 1984, 27, 11, 1457. |
【2】 Castaner, J.; Pento, J.T.; Octenidine hydrochloride. Drugs Fut 1986, 11, 4, 269. |
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