1-(4-cyclohexylphenyl)-1-ethanone -Drug Synthesis Database

【结构式】

【分子编号】21719

【品名】1-(4-cyclohexylphenyl)-1-ethanone

【CA登记号】18594-05-3

【分子式】C₁₄H₁₈O

【分子量】202.29632

【元素组成】C 83.12% H 8.97% O 7.91%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(I)

Title compound was prepared by Claisen Schmidt condensation of 4'-cyclohexylacetophenone (I) with 3,5-dimethoxybenzaldehyde (II) in EtOH using NaOH as the catalyst.

参考文献中间体

合成目标

【1】 Nielsen, S.F.; Christensen, S.B.; Gruciani, G.; Kharazmi, A.; Liljefors, T.; Antileishmanial chalcones: Statistical design, synthesis, and three-dimensional quantitative structure-activity relationship analysis. J Med Chem 1998, 41, 24, 4819.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	21719	1-(4-cyclohexylphenyl)-1-ethanone	18594-05-3	C₁₄H₁₈O	详情	详情
(II)	21720	3,5-dimethoxybenzaldehyde	7311-34-4	C₉H₁₀O₃	详情	详情

Extended Information