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【结 构 式】 
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【分子编号】66211 【品名】4-bromo-1-(4-nitrobenzoyl)-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 【CA登记号】 |
【 分 子 式 】C17H13BrN2O4 【 分 子 量 】389.205 【元素组成】C 52.46% H 3.37% Br 20.53% N 7.20% O 16.44% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)
| 【1】 Tsunoda T,Yamazaki A.et al.2003.vasopressin antagonist. Org Ptoc Res Dev,7 1 883~887 MatsuhisaA，Taniguchi N,et al.2000.Nonpeptide arginine vasopressin antagonists for both VIA and V2 receptors: synthesis and pharmacological properties of 4'-(1,4,5,6-tetrahydroimidazo[4,5-d] [1] benzazepine-6-carbonyl) benzanilide derivatives and 4’-(5,6-dihydro-4H-thiazolo[5,4-d] [1] benzazepint-6-carbonyl) benzanilide derivative. Chem Pharm Bull, 48, 21～31 |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 41811 | 1-(4-nitrobenzoyl)-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one | C17H14N2O4 | 详情 | 详情 | |
| (II) | 66211 | 4-bromo-1-(4-nitrobenzoyl)-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one | C17H13BrN2O4 | 详情 | 详情 | |
| (III) | 41818 | [2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl](4-nitrophenyl)methanone | C19H16N4O3 | 详情 | 详情 | |
| (IV) | 41819 | (4-aminophenyl)[2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl]methanone | C19H18N4O | 详情 | 详情 | |
| (VII) | 18506 | [1,1'-biphenyl]-2-carbonyl chloride | C13H9ClO | 详情 | 详情 |
Extended Information