(6R)-benzhydryl 8-oxo-7-(2-phenylacetamido)-3-((triphenylphosphoranylidene)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate -Drug Synthesis Database

【结构式】

【分子编号】66173

【品名】(6R)-benzhydryl 8-oxo-7-(2-phenylacetamido)-3-((triphenylphosphoranylidene)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

【CA登记号】　

【分子式】C₄₇H₃₉N₂O₄SP

【分子量】758.878

【元素组成】C 474.39% H 5.18% N 3.69% O 8.43% S 4.22% P 4.08%

与该中间体有关的原料药合成路线共 2 条

该中间体在本合成路线中的序号：(IV)

【1】 Kumar Y.Prasad M, SinghK.et aL 2005. Preparation of intermediates for the synthesis of 3-[2-(4-methylthiazole-5-yD vinyl] cephalosporins W0 2005100330

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	66171	Ethanone,1-(4-methyl-5-thiazolyl)-;Ketone,methyl 4-methyl-5-thiazolyl ;5-Acetyl-4-methylthiazole	38205-55-9	C₆H₇NOS	详情	详情
(II)	66172	5-Thiazolemethanol,4-methyl-;(4-Methylthiazol-5-yl)methanol;4-Methyl-5-(hydroxymethyl)thiazole;4-Methyl-5-thiazolemethanol	1977-06-6	C₅H₇NOS	详情	详情
(III)	11153	4-Methyl-1,3-thiazole-5-carbaldehyde	82294-70-0	C₅H₅NOS	详情	详情
(IV)	66173	(6R)-benzhydryl 8-oxo-7-(2-phenylacetamido)-3-((triphenylphosphoranylidene)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate		C₄₇H₃₉N₂O₄SP	详情	详情
(V)	66174	(6R,7R)-7-amino-3-((Z)-2-(4-methylthiazol-5-yl)vinyl)-8-oxo-1-azabicyclo[4.2.0]octane-2-carboxylic acid		C₁₄H₁₇N₃O₃S	详情	详情
(VI)	66175	(Z)-S-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate	94088-75-2	C₁₃H₁₀N₄O₂S₃	详情	详情

该中间体在本合成路线中的序号：(II)

【1】 Kumar Y.Prasad M Singh K, et al. 2005 .Intermediates useful in the synthesis d 3-(2-substituted-vinyl)cephalosporins W0 2005100367

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	66176	(6R)-benzhydryl 3-(chloromethyl)-8-oxo-7-(2-phenylacetamido)-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate		C₃₀H₂₇ClN₂O₄	详情	详情
(II)	66173	(6R)-benzhydryl 8-oxo-7-(2-phenylacetamido)-3-((triphenylphosphoranylidene)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate		C₄₇H₃₉N₂O₄SP	详情	详情
(III)	11153	4-Methyl-1,3-thiazole-5-carbaldehyde	82294-70-0	C₅H₅NOS	详情	详情
(IV)	66174	(6R,7R)-7-amino-3-((Z)-2-(4-methylthiazol-5-yl)vinyl)-8-oxo-1-azabicyclo[4.2.0]octane-2-carboxylic acid		C₁₄H₁₇N₃O₃S	详情	详情
(V)	66175	(Z)-S-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate	94088-75-2	C₁₃H₁₀N₄O₂S₃	详情	详情

Extended Information