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【结 构 式】 
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【分子编号】11635 【品名】(E)-3-(1,3-Benzodioxol-5-yl)-2-propenoyl chloride 【CA登记号】 |
【 分 子 式 】C10H7ClO3 【 分 子 量 】210.61648 【元素组成】C 57.03% H 3.35% Cl 16.83% O 22.79% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)3,4-Methylenedioxycinnamic acid (I) is transformed into the corresponding acid chloride (II) by treatment with oxalyl chloride in benzene. The acid chloride is then converted without purification into antiepilepsirine by treatment with piperidine in benzene.
| 【1】 Ruyun, J.; ANTIEPILEPSIRINE. Drugs Fut 1990, 15, 4, 331. |
| 【2】 Pei, Y.; Li, J.; Cai, Z.; Zhang, B.; Ku, B.; Pharmacological study of tablettae antiepilepticae I. Its effect on the CNS. Nat Med J China 1978, 58, 4, 216-9. |
| 【3】 Wang, S.; Li, R.; Liu, W.; et al.; Structure-anticonvulsant activity relationships of some cinnamamides of substituted aromatic ring. Acta Pharm Sin 1986, 21, 7, 542-5. |
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