(S)-tert-butyl 6,7-dimethoxy-1-(5-methyl-3-methylene-2-oxohexyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate -Drug Synthesis Database

【结构式】

【分子编号】67449

【品名】(S)-tert-butyl 6,7-dimethoxy-1-(5-methyl-3-methylene-2-oxohexyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

【CA登记号】　

【分子式】C₂₄H₃₅NO₅

【分子量】417.54564

【元素组成】C 69.04% H 8.45% N 3.35% O 19.16%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(VI)

【1】 Amarasinghe KKD, Rishel MJ, Dinn SR, et al.2009.Fluorinated dihydrotetrabenazine ether imaging agents and probes. US 2009/0110636 A1.
【2】 Rishel MJ, Amarasinghe KKD, Dinn SR, et al.2009.Asymmetric synthesis of tetrabenazine and dihydrotertabenazine, 74: 4001～4004.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(II)	67445	(S)-diisopropyl 2-(2-(tert-butoxycarbonyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)malonate		C₂₅H₃₇NO₈	详情	详情
(I)	67442	6,7-dimethoxy-3,4-dihydroisoquinoline	3382-18-1	C₁₁H₁₃NO₂	详情	详情
(III)	67446	（S)-tert-butyl 1-(2-isopropoxy-2-oxoethyl)-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate		C₂₁H₃₁NO₆	详情	详情
(IV)	67447	(S)-tert-butyl 6,7-dimethoxy-1-(2-oxoethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 5 C6H11I 2-iodo-4-methylpent-1-ene		C₁₈H₂₅NO₅	详情	详情
(V)	67448	2-iodo-4-methylpent-1-ene		C₆H₁₁I	详情	详情
(VI)	67449	(S)-tert-butyl 6,7-dimethoxy-1-(5-methyl-3-methylene-2-oxohexyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate		C₂₄H₃₅NO₅	详情	详情

Extended Information